For systems that crystallize readily, Express-Zen-Core 288™ is pre-plated as single compounds in the SWISSCI 3 Lens 96 well Crystallization Plate.
0.5ml of 200mM compound is dried down in each of the three drop positions (288 compounds total)
Dry compound eliminates need for organic co-solvent
Add 20ml of mother liquor to the well and up to 5ml of stabilization buffer to each drop for a 20mM soaking stock (lower volumes may be added for higher concentration soaks)
Powder re-supply available from Zenobia
An average of 40 analogues available for each fragment (SARbyCatalogue). Analogue plates available through Zenobia
Individual PDB files for all ligands are provided with purchase along with excel and SD files with structures/smiles and plate format
 
Compounds are plated in the SWISSCI 3 Lens 96 well crystallization plate, as shown. Every drop position is used with one compound dispensed in each of the three drops per well.  0.5ml of a 200mM compound stock is dried in each drop so that up to 5ml of stabilization buffer may be added per well for a 20mM soaking.